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HMB separates itself from other supplements with a growing body of research showing not only that HMB works to improve the results of an exercise program, but is also safe. In fact, the study of HMB safety has been just as extensive as the study of the effects of HMB on improving strength and performance. In the last 2 decades, about 50 human studies, 20 review articles, and 2 meta-analyses have been published as peer-reviewed papers, the scientific gold standard. The following research publications show how HMB benefits trained and untrained, men and women, young and older adults. The HMB research is broken into specific categories below. Click on an area of interest to see a detailed bibliography of HMB research.